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    • Hatch plugin for generating Python files from Protocol Buffers .proto files
      Python
      Other
      61410Updated Apr 21, 2026Apr 21, 2026
    • pomoxis

      Public
      Analysis components from Oxford Nanopore Research
      Python
      Other
      2297101Updated Apr 9, 2026Apr 9, 2026
    • medaka

      Public
      Sequence correction provided by ONT Research
      Python
      Other
      89506313Updated Apr 8, 2026Apr 8, 2026
    • pod5-file-format

      Public
      Pod5: a high performance file format for nanopore reads.
      C++
      Other
      37174502Updated Mar 31, 2026Mar 31, 2026
    • ont-output-specifications

      Public
      Specifications for output files from MinKNOW, dorado and others
      Python
      0600Updated Mar 18, 2026Mar 18, 2026
    • bonito

      Public
      A PyTorch Basecaller for Oxford Nanopore Reads
      Python
      Other
      13643042Updated Feb 20, 2026Feb 20, 2026
    • dorado

      Public
      Oxford Nanopore's Basecaller
      C++
      Other
      118820873Updated Feb 19, 2026Feb 19, 2026
    • ont-minimap2

      Public
      Cross platform builds for minimap2
      CMake
      3800Updated Feb 11, 2026Feb 11, 2026
    • modkit

      Public
      A bioinformatics tool for working with modified bases
      Rust
      Other
      272622824Updated Jan 19, 2026Jan 19, 2026
    • pyspoa

      Public
      Python bindings to spoa
      Python
      Other
      42230Updated Dec 3, 2025Dec 3, 2025
    • pomfret

      Public
      C
      22720Updated Nov 14, 2025Nov 14, 2025
    • Protobuf and gRPC specifications for the MinKNOW API
      Python
      Other
      1669402Updated Oct 29, 2025Oct 29, 2025
    • Blitzing Fast CTC Beam Search Decoder
      Rust
      MIT License
      2918631Updated Oct 27, 2025Oct 27, 2025
    • Dorado Documentation
      Python
      Other
      1700Updated Aug 4, 2025Aug 4, 2025
    • A curated list of awesome nanopore analysis tools.
      MIT License
      57000Updated Jul 2, 2025Jul 2, 2025
    • rerio

      Public
      Research release basecalling models and configurations
      Python
      Other
      1111741Updated May 21, 2025May 21, 2025
    • Python
      Other
      41371Updated May 2, 2025May 2, 2025
    • VBZ compression plugin for nanopore signal data
      C++
      Mozilla Public License 2.0
      1343211Updated Apr 7, 2025Apr 7, 2025
    • Homebrew casks for applications from Oxford Nanopore Technologies PLC and Metrichor Ltd.
      Ruby
      0700Updated Dec 24, 2024Dec 24, 2024
    • Read Until client library for Nanopore Sequencing
      Python
      Other
      1210800Updated Sep 25, 2024Sep 25, 2024
    • remora

      Public
      Methylation/modified base calling separated from basecalling.
      Python
      Other
      27186161Updated Sep 17, 2024Sep 17, 2024
    • sqlpad

      Public
      Web-based SQL editor run in your own private cloud. Supports MySQL, Postgres, SQL Server, Vertica, Crate, ClickHouse, Trino, Presto, SAP HANA, Cassandra, Snowfl…
      JavaScript
      MIT License
      814000Updated May 14, 2024May 14, 2024
    • Python
      Mozilla Public License 2.0
      61721Updated Mar 11, 2024Mar 11, 2024
    • ont_fast5_api

      Public
      Oxford Nanopore Technologies fast5 API software
      Python
      Other
      30155131Updated Feb 27, 2024Feb 27, 2024
    • pipeline-umi-amplicon

      Public
      Workflow to prepare high accuracy single molecule consensus sequences from amplicon data using unique molecular identifiers
      Python
      Other
      1435183Updated Feb 27, 2024Feb 27, 2024
    • ONT fork of Linux for NVIDIA Tegra based devices
      C
      Other
      1000Updated Jun 30, 2023Jun 30, 2023
    • kmer_models

      Public
      Predictive kmer models for development use
      Mozilla Public License 2.0
      206300Updated Jun 6, 2023Jun 6, 2023
    • Splitting of sequence reads by internal adapter sequence search
      Python
      Other
      851210Updated May 30, 2023May 30, 2023
    • megalodon

      Public
      Megalodon is a research command line tool to extract high accuracy modified base and sequence variant calls from raw nanopore reads by anchoring the informatio…
      Python
      Other
      27204470Updated May 4, 2023May 4, 2023
    • tombo

      Public
      Tombo is a suite of tools primarily for the identification of modified nucleotides from raw nanopore sequencing data.
      Python
      Other
      542341322Updated May 4, 2023May 4, 2023
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