AMP-SEMiner-Portal

A Data Portal for Antimicrobial Peptides from Metagenome-Assembled Genomes.

Introduction

This is the open-source code for the Data Portal(MAG-AMPome.aigene.org.cn) of our latest article Unveiling the Evolution of Antimicrobial Peptides in Gut Microbes via Foundation Model-Powered Framework.

AMP-SEMiner (Antimicrobial Peptide Structural Evolution Miner) is an AI-driven framework developed to identify antimicrobial peptides (AMPs) from metagenome-assembled genomes (MAGs). You can access the code for AMP-SEMiner at GitHub.

1.backend

1.1 use docker

backend_docker

1.2 use python

backend_python

2.frontend

1.1 use npm

frontend

in step 1.use npm run preview

1.2 use docker

frontend

in step 2.docker run

Citation

@article{LI2025115773,
title = {Unveiling the evolution of antimicrobial peptides in gut microbes via foundation-model-powered framework},
journal = {Cell Reports},
volume = {44},
number = {6},
pages = {115773},
year = {2025},
issn = {2211-1247},
doi = {https://doi.org/10.1016/j.celrep.2025.115773},
url = {https://www.sciencedirect.com/science/article/pii/S2211124725005443},
author = {Wenhui Li and Baicheng Huang and Menghao Guo and Zihan Zeng and Tao Cai and Linqing Feng and Xinpeng Zhang and Ling Guo and Xianyue Jiang and Yanbin Yin and Ercheng Wang and Xingxu Huang and Jinfang Zheng},
keywords = {antimicrobial peptides, protein language model, protein structure, evolution, human gut microbiota},

Contact

Menghao Guo: menghao.guo.319@gmail.com