diff --git a/server/datastore/mysql/policies.go b/server/datastore/mysql/policies.go
index 6bf39dfc976..5e03ef2b04f 100644
--- a/server/datastore/mysql/policies.go
+++ b/server/datastore/mysql/policies.go
@@ -1503,12 +1503,20 @@ func (ds *Datastore) ApplyPolicySpecs(ctx context.Context, authorID uint, specs
 					spec.Query = generated.Query
 				}
 
+				// patch_software_title_id is only for type=patch. Dynamic policies may still
+				// carry fleet_maintained_app_slug (e.g. install_software); they must not
+				// reuse the same title id or they collide on idx_team_id_patch_software_title_id.
+				var patchSoftwareTitleIDArg *uint
+				if spec.Type == fleet.PolicyTypePatch {
+					patchSoftwareTitleIDArg = fmaTitleID
+				}
+
 				res, err := tx.ExecContext(
 					ctx,
 					query,
 					spec.Name, spec.Query, spec.Description, authorID, spec.Resolution, teamID, spec.Platform, spec.Critical,
 					spec.CalendarEventsEnabled, softwareInstallerID, vppAppsTeamsID, scriptID, spec.ConditionalAccessEnabled,
-					spec.Type, fmaTitleID,
+					spec.Type, patchSoftwareTitleIDArg,
 				)
 				if err != nil {
 					return ctxerr.Wrap(ctx, err, "exec ApplyPolicySpecs insert")
diff --git a/server/datastore/mysql/policies_test.go b/server/datastore/mysql/policies_test.go
index ef8c6f790a7..90746781d3d 100644
--- a/server/datastore/mysql/policies_test.go
+++ b/server/datastore/mysql/policies_test.go
@@ -88,6 +88,7 @@ func TestPolicies(t *testing.T) {
 		{"ResetAttemptsOnFailingToPassingAsync", testResetAttemptsOnFailingToPassingAsync},
 		{"PolicyModificationResetsAttemptNumber", testPolicyModificationResetsAttemptNumber},
 		{"TeamPatchPolicy", testTeamPatchPolicy},
+		{"ApplyPolicySpecsDynamicAndPatchSameFMA", testApplyPolicySpecsDynamicAndPatchSameFMA},
 		{"TeamPolicyAutomationFilter", testTeamPolicyAutomationFilter},
 		{"BatchedPolicyMembershipCleanup", testBatchedPolicyMembershipCleanup},
 		{"BatchedPolicyMembershipCleanupOnPolicyUpdate", testBatchedPolicyMembershipCleanupOnPolicyUpdate},
@@ -7824,6 +7825,105 @@ func testTeamPatchPolicy(t *testing.T, ds *Datastore) {
 	require.NotEqual(t, previousChecksum, newChecksum)
 }
 
+// testApplyPolicySpecsDynamicAndPatchSameFMA is a regression test for a unique
+// index collision on (team_id, patch_software_title_id). A dynamic policy that
+// carries fleet_maintained_app_slug (e.g. install_software automation) must not
+// reuse the FMA's title id in patch_software_title_id, otherwise a separate
+// patch policy on the same team and FMA collides with it.
+func testApplyPolicySpecsDynamicAndPatchSameFMA(t *testing.T, ds *Datastore) {
+	ctx := context.Background()
+	user1 := test.NewUser(t, ds, "Alice", "alice@example.com", true)
+	team1, err := ds.NewTeam(ctx, &fleet.Team{Name: "team-fma-collision"})
+	require.NoError(t, err)
+
+	maintainedApp, err := ds.UpsertMaintainedApp(ctx, &fleet.MaintainedApp{
+		Name:             "Maintained1",
+		Slug:             "maintained1",
+		Platform:         "darwin",
+		UniqueIdentifier: "fleet.maintained1",
+	})
+	require.NoError(t, err)
+
+	_, fmaTitleID, err := ds.MatchOrCreateSoftwareInstaller(ctx, &fleet.UploadSoftwareInstallerPayload{
+		InstallScript:        "hello",
+		PreInstallQuery:      "SELECT 1",
+		PostInstallScript:    "world",
+		StorageID:            "storage-fma-collision",
+		Filename:             "maintained1",
+		Title:                "Maintained1",
+		Version:              "1.0",
+		Source:               "apps",
+		Platform:             "darwin",
+		BundleIdentifier:     "fleet.maintained1",
+		UserID:               user1.ID,
+		TeamID:               &team1.ID,
+		ValidatedLabels:      &fleet.LabelIdentsWithScope{},
+		FleetMaintainedAppID: &maintainedApp.ID,
+	})
+	require.NoError(t, err)
+
+	// Apply a dynamic install_software policy that references the FMA slug. With
+	// the bug, the FMA's title id was written into patch_software_title_id even
+	// though spec.Type was dynamic.
+	err = ds.ApplyPolicySpecs(ctx, user1.ID, []*fleet.PolicySpec{
+		{
+			Name:                   "install-fma-dynamic",
+			Query:                  "SELECT 1;",
+			Team:                   team1.Name,
+			Platform:               "darwin",
+			Type:                   fleet.PolicyTypeDynamic,
+			FleetMaintainedAppSlug: "maintained1",
+			SoftwareTitleID:        &fmaTitleID,
+		},
+	})
+	require.NoError(t, err)
+
+	// Apply a patch policy on the same team for the same FMA slug. With the bug
+	// this collided with the dynamic row on (team_id, patch_software_title_id).
+	err = ds.ApplyPolicySpecs(ctx, user1.ID, []*fleet.PolicySpec{
+		{
+			Name:                   "patch-fma",
+			Query:                  "SELECT 1;",
+			Team:                   team1.Name,
+			Type:                   fleet.PolicyTypePatch,
+			FleetMaintainedAppSlug: "maintained1",
+		},
+	})
+	require.NoError(t, err)
+
+	// Verify both policies exist and that patch_software_title_id is only set on
+	// the patch policy.
+	type policyRow struct {
+		Name                 string `db:"name"`
+		Type                 string `db:"type"`
+		PatchSoftwareTitleID *uint  `db:"patch_software_title_id"`
+	}
+	var rows []policyRow
+	ExecAdhocSQL(t, ds, func(q sqlx.ExtContext) error {
+		return sqlx.SelectContext(ctx, q, &rows,
+			`SELECT name, type, patch_software_title_id FROM policies WHERE team_id = ? ORDER BY type`,
+			team1.ID,
+		)
+	})
+	require.Len(t, rows, 2)
+
+	byType := make(map[string]policyRow, len(rows))
+	for _, r := range rows {
+		byType[r.Type] = r
+	}
+
+	dyn, ok := byType[fleet.PolicyTypeDynamic]
+	require.True(t, ok, "dynamic policy must be persisted")
+	require.Equal(t, "install-fma-dynamic", dyn.Name)
+	require.Nil(t, dyn.PatchSoftwareTitleID, "dynamic policy must not set patch_software_title_id")
+
+	patch, ok := byType[fleet.PolicyTypePatch]
+	require.True(t, ok, "patch policy must be persisted")
+	require.Equal(t, "patch-fma", patch.Name)
+	require.NotNil(t, patch.PatchSoftwareTitleID, "patch policy must set patch_software_title_id")
+	require.Equal(t, fmaTitleID, *patch.PatchSoftwareTitleID)
+}
+
 func testTeamPolicyAutomationFilter(t *testing.T, ds *Datastore) {
 	ctx := context.Background()
 	user1 := test.NewUser(t, ds, "Alice", "alice@example.com", true)