diff --git a/src/coreclr/pal/src/configure.cmake b/src/coreclr/pal/src/configure.cmake
index 8ada9b82c11ad9..9c284590e99f41 100644
--- a/src/coreclr/pal/src/configure.cmake
+++ b/src/coreclr/pal/src/configure.cmake
@@ -141,7 +141,18 @@ check_function_exists(vm_read HAVE_VM_READ)
 check_function_exists(semget HAS_SYSV_SEMAPHORES)
 check_function_exists(pthread_mutex_init HAS_PTHREAD_MUTEXES)
 check_function_exists(ttrace HAVE_TTRACE)
-check_function_exists(pipe2 HAVE_PIPE2)
+
+set(PREVIOUS_CMAKE_REQUIRED_FLAGS ${CMAKE_REQUIRED_FLAGS})
+if(CLR_CMAKE_HOST_APPLE)
+  set(CMAKE_REQUIRED_FLAGS "${CMAKE_REQUIRED_FLAGS} -Werror=unguarded-availability-new")
+endif()
+check_cxx_symbol_exists(pipe2 unistd.h PAL_HAVE_PIPE2)
+if(PAL_HAVE_PIPE2)
+  set(HAVE_PIPE2 1 CACHE INTERNAL "" FORCE)
+else()
+  set(HAVE_PIPE2 0 CACHE INTERNAL "" FORCE)
+endif()
+set(CMAKE_REQUIRED_FLAGS ${PREVIOUS_CMAKE_REQUIRED_FLAGS})
 
 check_cxx_source_compiles("
 #include <pthread_np.h>