diff --git a/ext/spl/ArrayObjectBuiltin.php b/ext/spl/ArrayObjectBuiltin.php
index 4c74e9abb48..c97f1869a6b 100644
--- a/ext/spl/ArrayObjectBuiltin.php
+++ b/ext/spl/ArrayObjectBuiltin.php
@@ -206,9 +206,6 @@ public function execute(Frame $frame): void
             0,
             'iteratorClass'
         );
-        if (null === $frame->returnVar) {
-            return;
-        }
         $entry = VmReflection::resolveClassEntry($frame->vmContext, $iteratorClass);
         if (null === $entry
             || !InterfaceCheck::entryIsInstanceOf($entry, ArrayIteratorBuiltin::CLASS_LC, $frame->vmContext)) {
diff --git a/lib/Compiler.php b/lib/Compiler.php
index 694e95242fc..9aab4a631ba 100755
--- a/lib/Compiler.php
+++ b/lib/Compiler.php
@@ -12778,7 +12778,41 @@ private function precedingInlineCallArgProducersBeforeCfgOp(array $cfgChildren,
             array_unshift($producers, $child);
         }
 
-        return $producers;
+        return $this->filterDeadVoidStatementMethodCallProducers($producers);
+    }
+
+    /**
+     * Drop void statement MethodCalls before a sibling MethodCall inline call-arg (#10778).
+     *
+     * php-cfg: `$ao->setIteratorClass('X'); echo var_export($ao->getIteratorClass(), true);`
+     * hoists both MethodCalls; the void setter must not map to var_export arg 0.
+     *
+     * @param list<Op\Expr> $producers
+     *
+     * @return list<Op\Expr>
+     */
+    private function filterDeadVoidStatementMethodCallProducers(array $producers): array
+    {
+        if (\count($producers) < 2) {
+            return $producers;
+        }
+        $filtered = [];
+        $count = \count($producers);
+        for ($i = 0; $i < $count; ++$i) {
+            $producer = $producers[$i];
+            if (
+                $producer instanceof Op\Expr\MethodCall
+                && property_exists($producer, 'result')
+                && empty($producer->result->usages)
+                && $i + 1 < $count
+                && $producers[$i + 1] instanceof Op\Expr\MethodCall
+            ) {
+                continue;
+            }
+            $filtered[] = $producer;
+        }
+
+        return $filtered;
     }
 
     /**
diff --git a/test/compliance/cases/stdlib/arrayobject_getiterator_after_set.phpt b/test/compliance/cases/stdlib/arrayobject_getiterator_after_set.phpt
new file mode 100644
index 00000000000..ff23f9a74ba
--- /dev/null
+++ b/test/compliance/cases/stdlib/arrayobject_getiterator_after_set.phpt
@@ -0,0 +1,14 @@
+--TEST--
+stdlib ArrayObject::getIteratorClass() after void setIteratorClass() in var_export expr (#10778, ext/spl/spl_array.c)
+--FILE--
+<?php
+declare(strict_types=1);
+$ao = new ArrayObject([1, 2, 3]);
+$ao->setIteratorClass('ArrayIterator');
+echo var_export($ao->getIteratorClass(), true), "\n";
+if ('ArrayIterator' !== $ao->getIteratorClass()) {
+    exit(1);
+}
+?>
+--EXPECT--
+'ArrayIterator'
diff --git a/test/repro/maintainer_gap_arrayobject_getiterator_after_set.php b/test/repro/maintainer_gap_arrayobject_getiterator_after_set.php
new file mode 100644
index 00000000000..b970354eef1
--- /dev/null
+++ b/test/repro/maintainer_gap_arrayobject_getiterator_after_set.php
@@ -0,0 +1,8 @@
+<?php
+declare(strict_types=1);
+$ao = new ArrayObject([1, 2, 3]);
+$ao->setIteratorClass('ArrayIterator');
+echo var_export($ao->getIteratorClass(), true), "\n";
+if ('ArrayIterator' !== $ao->getIteratorClass()) {
+    exit(1);
+}