diff --git a/.github/workflows/pythonapp-min.yml b/.github/workflows/pythonapp-min.yml
new file mode 100644
index 0000000000..2918d13d5c
--- /dev/null
+++ b/.github/workflows/pythonapp-min.yml
@@ -0,0 +1,170 @@
+name: build-min
+
+on:
+  # quick tests for pull requests and the releasing branches
+  push:
+    branches:
+      - dev
+      - main
+      - releasing/*
+  pull_request:
+
+concurrency:
+  # automatically cancel the previously triggered workflows when there's a newer version
+  group: build-min-${{ github.event.pull_request.number || github.ref }}
+  cancel-in-progress: true
+
+jobs:
+  # caching of these jobs:
+  #   - docker-py3-pip- (shared)
+  #   - ubuntu py37 pip-
+  #   - os-latest-pip- (shared)
+  min-dep-os:  # min dependencies installed tests for different OS
+    runs-on: ${{ matrix.os }}
+    strategy:
+      fail-fast: false
+      matrix:
+        os: [windows-latest, macOS-latest, ubuntu-latest]
+    timeout-minutes: 40
+    steps:
+    - uses: actions/checkout@v2
+    - name: Set up Python 3.8
+      uses: actions/setup-python@v2
+      with:
+        python-version: 3.8
+    - name: Prepare pip wheel
+      run: |
+        which python
+        python -m pip install --upgrade pip wheel
+    - name: cache weekly timestamp
+      id: pip-cache
+      run: |
+        echo "::set-output name=datew::$(date '+%Y-%V')"
+        echo "::set-output name=dir::$(pip cache dir)"
+      shell: bash
+    - name: cache for pip
+      uses: actions/cache@v2
+      id: cache
+      with:
+        path: ${{ steps.pip-cache.outputs.dir }}
+        key: ${{ matrix.os }}-latest-pip-${{ steps.pip-cache.outputs.datew }}
+    - if: runner.os == 'windows'
+      name: Install torch cpu from pytorch.org (Windows only)
+      run: |
+        python -m pip install torch==1.9.1+cpu -f https://download.pytorch.org/whl/torch_stable.html
+    - name: Install the dependencies
+      run: |
+        # min. requirements
+        python -m pip install torch==1.9.1
+        python -m pip install -r requirements-min.txt
+        python -m pip list
+        BUILD_MONAI=0 python setup.py develop  # no compile of extensions
+      shell: bash
+    - name: Run quick tests (CPU ${{ runner.os }})
+      run: |
+        python -c 'import torch; print(torch.__version__); print(torch.rand(5,3))'
+        python -c "import monai; monai.config.print_config()"
+        ./runtests.sh --min
+      shell: bash
+      env:
+        QUICKTEST: True
+
+  min-dep-py3:  # min dependencies installed tests for different python
+    runs-on: ubuntu-latest
+    strategy:
+      fail-fast: false
+      matrix:
+        python-version: [3.6, 3.7, 3.8, 3.9]
+    timeout-minutes: 40
+    steps:
+    - uses: actions/checkout@v2
+    - name: Set up Python ${{ matrix.python-version }}
+      uses: actions/setup-python@v2
+      with:
+        python-version: ${{ matrix.python-version }}
+    - name: Prepare pip wheel
+      run: |
+        which python
+        python -m pip install --user --upgrade pip setuptools wheel
+    - name: cache weekly timestamp
+      id: pip-cache
+      run: |
+        echo "::set-output name=datew::$(date '+%Y-%V')"
+        echo "::set-output name=dir::$(pip cache dir)"
+      shell: bash
+    - name: cache for pip
+      uses: actions/cache@v2
+      id: cache
+      with:
+        path: ${{ steps.pip-cache.outputs.dir }}
+        key: ubuntu-latest-latest-pip-${{ steps.pip-cache.outputs.datew }}
+    - name: Install the dependencies
+      run: |
+        # min. requirements
+        python -m pip install torch==1.9.1
+        python -m pip install -r requirements-min.txt
+        python -m pip list
+        BUILD_MONAI=0 python setup.py develop  # no compile of extensions
+      shell: bash
+    - name: Run quick tests (CPU ${{ runner.os }})
+      run: |
+        python -c 'import torch; print(torch.__version__); print(torch.rand(5,3))'
+        python -c "import monai; monai.config.print_config()"
+        ./runtests.sh --min
+      env:
+        QUICKTEST: True
+
+  min-dep-pytorch:  # min dependencies installed tests for different pytorch
+    runs-on: ubuntu-latest
+    strategy:
+      fail-fast: false
+      matrix:
+        pytorch-version: [1.5.1, 1.6.0, 1.7.1, 1.8.1, latest]
+    timeout-minutes: 40
+    steps:
+    - uses: actions/checkout@v2
+    - name: Set up Python 3.8
+      uses: actions/setup-python@v2
+      with:
+        python-version: 3.8
+    - name: Prepare pip wheel
+      run: |
+        which python
+        python -m pip install --user --upgrade pip setuptools wheel
+    - name: cache weekly timestamp
+      id: pip-cache
+      run: |
+        echo "::set-output name=datew::$(date '+%Y-%V')"
+        echo "::set-output name=dir::$(pip cache dir)"
+      shell: bash
+    - name: cache for pip
+      uses: actions/cache@v2
+      id: cache
+      with:
+        path: ${{ steps.pip-cache.outputs.dir }}
+        key: ubuntu-latest-latest-pip-${{ steps.pip-cache.outputs.datew }}
+    - name: Install the dependencies
+      run: |
+        # min. requirements
+        if [ ${{ matrix.pytorch-version }} == "latest" ]; then
+          python -m pip install torch
+        elif [ ${{ matrix.pytorch-version }} == "1.5.1" ]; then
+          python -m pip install torch==1.5.1
+        elif [ ${{ matrix.pytorch-version }} == "1.6.0" ]; then
+          python -m pip install torch==1.6.0
+        elif [ ${{ matrix.pytorch-version }} == "1.7.1" ]; then
+          python -m pip install torch==1.7.1
+        elif [ ${{ matrix.pytorch-version }} == "1.8.1" ]; then
+          python -m pip install torch==1.8.1
+        fi
+        python -m pip install -r requirements-min.txt
+        python -m pip list
+        BUILD_MONAI=0 python setup.py develop  # no compile of extensions
+      shell: bash
+    - name: Run quick tests (pytorch ${{ matrix.pytorch-version }})
+      run: |
+        python -c 'import torch; print(torch.__version__); print(torch.rand(5,3))'
+        python -c "import monai; monai.config.print_config()"
+        ./runtests.sh --min
+      env:
+        QUICKTEST: True
diff --git a/.github/workflows/pythonapp.yml b/.github/workflows/pythonapp.yml
index 28a9f34839..c10fed5ef3 100644
--- a/.github/workflows/pythonapp.yml
+++ b/.github/workflows/pythonapp.yml
@@ -106,101 +106,6 @@ jobs:
       env:
         QUICKTEST: True
 
-  min-dep-os:  # min dependencies installed tests for different OS
-    runs-on: ${{ matrix.os }}
-    strategy:
-      fail-fast: false
-      matrix:
-        os: [windows-latest, macOS-latest, ubuntu-latest]
-    timeout-minutes: 40
-    steps:
-    - uses: actions/checkout@v2
-    - name: Set up Python 3.8
-      uses: actions/setup-python@v2
-      with:
-        python-version: 3.8
-    - name: Prepare pip wheel
-      run: |
-        which python
-        python -m pip install --upgrade pip wheel
-    - name: cache weekly timestamp
-      id: pip-cache
-      run: |
-        echo "::set-output name=datew::$(date '+%Y-%V')"
-        echo "::set-output name=dir::$(pip cache dir)"
-      shell: bash
-    - name: cache for pip
-      uses: actions/cache@v2
-      id: cache
-      with:
-        path: ${{ steps.pip-cache.outputs.dir }}
-        key: ${{ matrix.os }}-latest-pip-${{ steps.pip-cache.outputs.datew }}
-    - if: runner.os == 'windows'
-      name: Install torch cpu from pytorch.org (Windows only)
-      run: |
-        python -m pip install torch==1.9.1+cpu -f https://download.pytorch.org/whl/torch_stable.html
-    - name: Install the dependencies
-      run: |
-        # min. requirements
-        python -m pip install torch==1.9.1
-        python -m pip install -r requirements-min.txt
-        python -m pip list
-        BUILD_MONAI=0 python setup.py develop  # no compile of extensions
-      shell: bash
-    - name: Run quick tests (CPU ${{ runner.os }})
-      run: |
-        python -c 'import torch; print(torch.__version__); print(torch.rand(5,3))'
-        python -c "import monai; monai.config.print_config()"
-        ./runtests.sh --min
-      shell: bash
-      env:
-        QUICKTEST: True
-
-  min-dep-py3:  # min dependencies installed tests for different python
-    runs-on: ubuntu-latest
-    strategy:
-      fail-fast: false
-      matrix:
-        python-version: [3.6, 3.7, 3.8, 3.9]
-    timeout-minutes: 40
-    steps:
-    - uses: actions/checkout@v2
-    - name: Set up Python ${{ matrix.python-version }}
-      uses: actions/setup-python@v2
-      with:
-        python-version: ${{ matrix.python-version }}
-    - name: Prepare pip wheel
-      run: |
-        which python
-        python -m pip install --user --upgrade pip setuptools wheel
-    - name: cache weekly timestamp
-      id: pip-cache
-      run: |
-        echo "::set-output name=datew::$(date '+%Y-%V')"
-        echo "::set-output name=dir::$(pip cache dir)"
-      shell: bash
-    - name: cache for pip
-      uses: actions/cache@v2
-      id: cache
-      with:
-        path: ${{ steps.pip-cache.outputs.dir }}
-        key: ubuntu-latest-latest-pip-${{ steps.pip-cache.outputs.datew }}
-    - name: Install the dependencies
-      run: |
-        # min. requirements
-        python -m pip install torch==1.9.1
-        python -m pip install -r requirements-min.txt
-        python -m pip list
-        BUILD_MONAI=0 python setup.py develop  # no compile of extensions
-      shell: bash
-    - name: Run quick tests (CPU ${{ runner.os }})
-      run: |
-        python -c 'import torch; print(torch.__version__); print(torch.rand(5,3))'
-        python -c "import monai; monai.config.print_config()"
-        ./runtests.sh --min
-      env:
-        QUICKTEST: True
-
   packaging:
     runs-on: ubuntu-latest
     env: