diff --git a/src/libs/API/index.ts b/src/libs/API/index.ts
index 0ba6391d21bc..16405e45ff9d 100644
--- a/src/libs/API/index.ts
+++ b/src/libs/API/index.ts
@@ -7,7 +7,7 @@ import {isOffline} from '@libs/Network/NetworkStore';
 import {push as pushToSequentialQueue, waitForIdle as waitForSequentialQueueIdle} from '@libs/Network/SequentialQueue';
 import Pusher from '@libs/Pusher';
 import {processWithMiddleware, use} from '@libs/Request';
-import {getLength as getPersistedRequestsLength} from '@userActions/PersistedRequests';
+import {getAll, getLength as getPersistedRequestsLength} from '@userActions/PersistedRequests';
 import CONST from '@src/CONST';
 import type OnyxRequest from '@src/types/onyx/Request';
 import type {PaginatedRequest, PaginationConfig, RequestConflictResolver} from '@src/types/onyx/Request';
@@ -62,8 +62,15 @@ function prepareRequest<TCommand extends ApiCommand>(
 ): OnyxRequest {
     Log.info('[API] Preparing request', false, {command, type});
 
+    let shouldApplyOptimisticData = true;
+    if (conflictResolver?.checkAndFixConflictingRequest) {
+        const requests = getAll();
+        const {conflictAction} = conflictResolver.checkAndFixConflictingRequest(requests);
+        shouldApplyOptimisticData = conflictAction.type !== 'noAction';
+    }
+
     const {optimisticData, ...onyxDataWithoutOptimisticData} = onyxData;
-    if (optimisticData) {
+    if (optimisticData && shouldApplyOptimisticData) {
         Log.info('[API] Applying optimistic data', false, {command, type});
         Onyx.update(optimisticData);
     }
diff --git a/src/libs/actions/Report.ts b/src/libs/actions/Report.ts
index 142b6d8fb9bc..9eccc1dc47fa 100644
--- a/src/libs/actions/Report.ts
+++ b/src/libs/actions/Report.ts
@@ -197,6 +197,7 @@ import {clearByKey} from './CachedPDFPaths';
 import {setDownload} from './Download';
 import {close} from './Modal';
 import navigateFromNotification from './navigateFromNotification';
+import {getAll} from './PersistedRequests';
 import {buildAddMembersToWorkspaceOnyxData, buildRoomMembersOnyxData} from './Policy/Member';
 import {createPolicyExpenseChats} from './Policy/Policy';
 import {
@@ -1106,9 +1107,14 @@ function openReport(
     const isInviteOnboardingComplete = introSelected?.isInviteOnboardingComplete ?? false;
     const isOnboardingCompleted = onboarding?.hasCompletedGuidedSetupFlow ?? false;
 
+    // Some cases we can have two open report requests with guide setup data because isInviteOnboardingComplete is not updated completely.
+    // Then we need to check the list request and prevent the guided setup data from being duplicated.
+    const allPersistedRequests = getAll();
+    const hasOpenReportWithGuidedSetupData = allPersistedRequests.some((request) => request.command === WRITE_COMMANDS.OPEN_REPORT && request.data?.guidedSetupData);
+
     // Prepare guided setup data only when nvp_introSelected is set and onboarding is not completed
     // OldDot users will never have nvp_introSelected set, so they will not see guided setup messages
-    if (introSelected && !isOnboardingCompleted && !isInviteOnboardingComplete) {
+    if (introSelected && !isOnboardingCompleted && !isInviteOnboardingComplete && !hasOpenReportWithGuidedSetupData) {
         const {choice, inviteType} = introSelected;
         const isInviteIOUorInvoice = inviteType === CONST.ONBOARDING_INVITE_TYPES.IOU || inviteType === CONST.ONBOARDING_INVITE_TYPES.INVOICE;
         const isInviteChoiceCorrect = choice === CONST.ONBOARDING_CHOICES.ADMIN || choice === CONST.ONBOARDING_CHOICES.SUBMIT || choice === CONST.ONBOARDING_CHOICES.CHAT_SPLIT;